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¹û¶³Ó°Ôº Institute of Cardiovascular Science

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Centre for Morphology and Structural Heart Disease

Ìý

Lead:

Group Members: Miss Chloe Li (PhD student), Miss Vaish Sabarigirivasan (MBPhD student).ÌýAdrian Crucean, George Belitsis &ÌýAigerim Mullen (Hon lecturers)

Location: Research Dept ofÌýChildren's Cardiovascular Disease,ÌýZayed Centre for Research, 20 Guilford Street, London, WC1N 1DZ

Overview:Ìý

Our group focusses on the structural architecture of the heart in congenital and acquired disease from embryonic/fetalÌýdevelopment through to adulthood.

At a cross-cutting level we provide expertise and advice on cardiovascular structure for a wide range of projects from animal models, prenatal diagnosis and treatment, to surgery; to anatomy for device design or simulation.

Specific areas of current research are: Deep-phenotyping of congenital and structural heart disease with current focus onÌýheart muscle disease (cardiomyopathy); Single ventricle disease;Ìýtetralogy of Fallot; and animal models of disease. Novel research techniques developed or in use in our lab include synchrotron-based multiscale orÌýHierarchical Phase-Contrast Tomography (HiP-CT); Contrast enhanced microCT; and High Resolution Episcopic Microscopy; and Virtual/ImmersiveÌýReality education.

We work closely with medical device developers, helping them to understand variations in morphologic substratesÌýin advance of device design, testing and pre-implant training.

Throughout the year, we run discrete modules for iBSC and MSc degrees in Cardiovascular Science and run short courses. We can design bespoke courses for organisations and external companies on request.

Highlights:

Our unit was instrumental in the development of bothÌýadult and paediatric echocardiographic training simulators. We provideÌýthe anatomic expertise to ensure the model is anatomically accurate.

Contact details: a.cook@ucl.ac.uk

Booking:
Hands-on Courses

Websites:

Twitter:
@¹û¶³Ó°ÔºHeartAcademy

Publications