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This module helps you to understand the basics of cancer biology. This includes awareness that cancer is a disease arising from the accumulation of genetic damage to cells, which through selective pressures give rise to specific phenotypic hallmarks of cancer.

The first part of this module introduces you to basic cancer biology explaining the cellular changes occurring during cancer development, the key genes, proteins and signalling pathways that regulate oncogenesis, and the carcinogenic mechanisms leading to cancer-associated mutations.

The second part of this module teaches you about different resources for cancer research, including various animal model systems used in the investigation of cancer, online tools and databases for analysis of cancer genomics, and basic experimental techniques used in the analysis of cancer. You will apply some of this knowledge through laboratory practicals to practice basic lab techniques, and bioinformatics workshops utilising online genomic tools.

This module will consist of a mixture of lectures, interactive tutorials, lab practicals, computer workshops and self-directed learning. You will also attend research-in-progress seminars from PhD students and postdoctoral researchers. Topics in this module include:

• Tumour Evolution,ÌýCancer EpidemiologyÌýand the Cancer Hallmarks
• Cancer Pathology
• The Regulation of Cell Cycle and Uncontrolled Proliferation
• The Mechanisms of Carcinogenesis
• Cell Signalling Pathways Regulating Cell Cycle
• Mechanisms of Gene Regulation
• Online Tools and Databases for Cancer Genomic Analysis
• Animal Models for Cancer Research
• Basic Experimental Techniques for Cancer Research