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Description
This module covers aspects of basic genetics, commonly used cytogenetic and molecular, laboratory techniques. It also includes lectures on the classification of chromosomes, meiosis, Mendelian inheritance, , linkage, strategies for a wide range of rapid genetic analysis techniques as well as high throughput sequencing techniques. The use of different array platforms, proteomics, functional assays and animal models as approaches to determining gene function or biological mechanisms will also be demonstrated.听
After taking this module you should be able to:听
- Demonstrate a working knowledge of meiosis and understand Mendelian inheritance;听
- Understand how chromosomal abnormalities and DNA sequence variants can occur and understand the consequences of such changes;
- Demonstrate an understanding of the principles of techniques used to study chromosomes, DNA and proteins and to acquire skills to practically apply some of these techniques.
The module comprises lectures, practical sessions and tutorials with dedicated tutorials covering linkage to help students understand the relevance of linkage analysis in genetic testing 听and critical analysis of research papers relating to the introduction of new technologies into clinical practice. You will have 听qPCR and immunohistochemistry practicals to gain insight into good laboratory practice, including designing an experiment, following a protocol, recording and analysing results, and making conclusions.听
Introductory Reading:听
Strachan T and Read A (2011) Human Molecular Genetics 5th edition听
Module deliveries for 2024/25 academic year
Last updated
This module description was last updated on 8th April 2024.
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