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Description
The focus of this module is on the biology of cancer cells, and statistical methodology used to describe and evaluate cancer treatments, using lung and breast cancer as the principal examples.听
The module introduces you to the epidemiology and cellular and molecular basis of cancer: how these features relate to the natural history of the disease, may be used for disease stratification, and guide treatment strategies; for example, how drugs can be used to target specific genetic mutations, and how immune responses can be co-opted to treat the disease. The module also explains the response of biological systems to radiation, and therefore why different radiation schedules may be used in cancer treatment.听听
This module provides an introduction to the principles of evidence based medicine, medical statistics as applied to cancer, and the design and conduct of clinical trials in cancer, ranging from early phase trials to assess the toxicity of new agents, through to large randomised studies comparing the efficacy of different treatment schedules, and innovative trial design. The critical appraisal of papers is key to this.听听
These basic science concepts will be explained against a backdrop of the clinical features and management strategies used in lung and breast cancers.
Module deliveries for 2024/25 academic year
Last updated
This module description was last updated on 8th April 2024.
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