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Content and Module Aims:

The aim of CELL0017 is to introduce students - with a good grounding in cellular and molecular biology - to the power of cross-disciplinary research. The contribution of chemists, microbiologists, immunologists and physicists to solving cell biological problems will be discussed. The module emphasises the relationship between the chemical scale and more complex levels of organisation in cells, and the balance of interactions required for cellular function. It explicitly recognises the different understandings of cell biology in different branches of biosciences, including virology and microbiology in health and disease.

The module will build on CELL009, CELL0010, and CELL0023 and supplement and reinforce CELL0016 Advanced Molecular Cell Biology and/or PHOL0008 Cell Signalling in Health and Disease. CELL0017 aims to appeal to students on strong interdisciplinary programmes, who will be very well placed to appreciate and comprehend the broad remit.

Through consideration of evidence, students will acquire a good broad knowledge of the principles and practice of modern cell biology. They should be able to use this knowledge to enhance their understanding and appreciation of other aspects of molecular life sciences.

Indicative lecture list (based on the syllabus from the last couple of years):

• Origin of Life (bacteria and archaea)
• Origin of Life (eukaryotes )
• Scarring, fibrosis and mechanobiology (2 lectures)
• Model Systems and Disease State
• Uncovering hidden information in databases
• Dementia and heart disease in yeast
• High throughput screening to probe EGFR signalling
• Imaging and homeostasis
• Modelling Epithelia
• The control of tissue size and shape
• "What I find cool in Cell Biology".