Preformulation (PHAY0032)

Key information

Faculty: Faculty of Life Sciences
Teaching department: School of Pharmacy
Credit value: 15

Restrictions: Only available to students on MSc PFE, MSc Pharmaceutics, and MRes Drug Sciences
Timetable

Alternative credit options

There are no alternative credit options available for this module.

Description

The course will give an overview of the basic information required to build up a picture of the physicochemical properties of a potential drug candidate and how this information is used to (i) make a decision on the likely developability of a compound and (ii) inform and direct likely formulation strategy. Key concepts to be introduced include solubility, partitioning, acid-base chemistry, dissolution behavior and effect of physical form. The use of the data to inform formulation strategy will be achieved with reference to case studies of marketed products and/or generic drug delivery devices.

List of lectures:

Introduction to preformulation
Solubility
Dissolution & partitioning
Crystalline materials
Pseudopolymorphs
Amorphous materials
Salts
Solid amorphous dispersions
Workshop: Problem-based learning on preformulation

Module deliveries for 2024/25 academic year

Intended teaching term: Term 1 听听听 Postgraduate (FHEQ Level 7)

Teaching and assessment

Mode of study: In person
Methods of assessment: 50% Coursework

50% Fixed-time remote activity
Mark scheme: Numeric Marks

Other information

Number of students on module in previous year: 49
Module leader: Professor Simon Gaisford
Who to contact for more information: sop.pgt@ucl.ac.uk

Last updated

This module description was last updated on 8th April 2024.

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Important information

The catalogue has been updated with key information about the modules that will run during the 2024/25 academic session. Current and prospective students can browse through the catalogue to consider possible module choices for the coming year.

Please note,听information in the catalogue is听subject to change as teaching and assessment arrangements for 2024/25 may need to be adjusted in line with the University's Feedback and Assessment principles and operating model.

Centrally managed exam durations will be provided on students' individual exam timetables. Arrangements for locally managed exams and in-class activity will be confirmed by the teaching department for the module.

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