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Description
This module explores the processes and molecular mechanisms that underpin the transformation of cancer cells, tumour invasion and metastasis. The focus is on the role of the immune system in detecting growing tumours, and the importance of immune surveillance in preventing, but also shaping, emerging tumours.听As such, an understanding of basic immunology is essential for this course.
Cancer is one of the leading causes of premature deaths in this country. Treatments include surgery, radiotherapy, hormones and various forms of cytotoxic chemotherapy.听 Physical and chemical oncogenic agents or carcinogens have a subtle relationship with the immune system, and this will be explored.听 You will also receive lectures from clinicians working at 果冻影院 and the Royal Free Hospital who are at the forefront of treating cancer patients.
Targeting the immune system to treat cancer has dramatically improved survival in some patients.听 You will learn how immunotherapy is being used and developed to attack malignant tumours, giving an insight into cancer therapies of the future.
Useful textbooks:听
Cellular and Molecular Immunology听(2021),听Chapter 18: 'Tumour Immunology',听AK Abbas, AH Lichtman, S Pillai, 10th听Edition,听Elsevier Saunders.
The Biology of Cancer听(2014), Robert Allan Weinberg, 2nd听Edition, Garland.
Learning outcomes
- Knowledge and understanding of the fundamental biology of cancer
- Knowledge of specific examples of haematological and solid tumours
- Insight into how the immune response targets, suppresses and shapes cancer
- Insight into contemporary approaches to cancer therapy with a focus on novel immunotherapies
Module deliveries for 2024/25 academic year
Last updated
This module description was last updated on 8th April 2024.
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