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果冻影院 and F-Prime launch Orchard Therapeutics to treat rare childhood diseases
3 May 2016
果冻影院 Business, the technology transfer company of 果冻影院, and venture capital firm F-Prime Capital Partners have launched Orchard Therapeutics, a biotechnology company specialising in gene therapies for life threatening rare childhood diseases.
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Orchard Therapeutics has secured 拢21 million investment led by F-Prime to support the development of gene therapy treatments for a range of diseases.
As part of its launch, Orchard announced formal partnerships with 果冻影院, Great Ormond Street Hospital for Children NHS Foundation Trust (GOSH), University of California Los Angeles (果冻影院A), The University of Manchester, Boston Children's Hospital for the development of these transformative gene therapies.
Orchard's lead programme is for the treatment of the rare and fatal disorder called severe combined immunodeficiency caused by adenosine deaminase deficiency (ADA-SCID), sometimes referred to as "bubble baby" syndrome in the press. Children with the disorder must be protected from any infections due to their highly fragile immune system.
In a first-in-man clinical study, global leaders in the field at 果冻影院/GOSH and 果冻影院A have shown significant immune reconstitution and 100% survival in 32 patients treated, as of March 2016.
Orchard's financing has been led by F-Prime Capital, with support from 果冻影院B and additional participation from the 果冻影院 Technology Fund.
Cengiz Tarhan, Managing Director of 果冻影院B, said:
"We are very excited to see 果冻影院's breakthrough treatments move forward in a commercial environment in a way that will benefit patients globally. The formation of Orchard represents the culmination of decades of research at 果冻影院 and its partners and we are delighted to be able to work with F-Prime Capital to launch Orchard."
The work at the 果冻影院 Institute of Child Health has been developed through the laboratories of Professors Bobby Gaspar, Adrian Thrasher and Waseem Qasim in collaboration with GOSH, 果冻影院A and King's College London, with funding and support from the National Institute for Health Research Biomedical Research Centre at Great Ormond Street Hospital for Children NHS Trust and 果冻影院, the Great Ormond Street Hospital Children's Charity, the Medical Research Council, the Wellcome Trust and the Histiocytosis Research Trust.听
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