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Leading 果冻影院 scientist joins major new alliance to map spread of coronavirus

23 March 2020

Professor Judith Breuer, Director of 果冻影院 Pathogen Genomics Unit (果冻影院-PGU), has today been announced as one of the leading UK scientists to be part of a major new genome sequencing consortium which will map the spread of Covid-19.

Corona

Covid-19 Genomics UK Consortium comprises of the NHS, Public Health Agencies, Wellcome Sanger Institute, and numerous academic institutions including 果冻影院. It will deliver large scale, rapid sequencing to better understand the spread of Covid-19 and share this intelligence with hospitals, regional NHS centres and the Government.

Samples from patients with confirmed cases of Covid-19 will be sent to a network of sequencing centres which currently includes Belfast, Birmingham, Cambridge, Cardiff, Edinburgh, Exeter, Glasgow, Liverpool, London, Norwich, Nottingham, Oxford and Sheffield.

By looking at the whole virus genome in people who have had confirmed cases of Covid-19, scientists can monitor changes in the virus at a national scale to understand how the virus is spreading and whether different strains are emerging. This will help plan public health interventions, contributing to improving clinical care of patients and the saving of lives.

Today, the Government and the UK鈥檚 Chief Scientific Adviser Sir Patrick Vallance, unveiled 拢20 million investment to support the consortium in looking for breakthroughs that help the UK respond to this and future pandemics, and save lives.

果冻影院, which, for over 10 years, has been a world leader in viral genome sequencing, will play a key role in sequencing viruses from the London area which is currently experiencing the highest numbers of hospitalised cases. Based in 果冻影院鈥檚 Zayed Centre for Research, Professor Breuer will be leading this work, closely supported by colleagues in the co-located 果冻影院 Genomics (Led by Dr Sergi Castellano).

Professor Breuer said: 鈥淐ovid-19 is major threat to London and the entire world. We at 果冻影院 are incredibly proud to be part of the national rapid response efforts to contain the virus. The Covid-19 Genomics UK Consortium will provide important data to Public Health England about how the virus is spreading. Viral sequencing provides a new tool which will aid national public health efforts to interrupt the spread of the virus.

鈥淏ased in the heart of London, 果冻影院 is uniquely placed to respond to this because of our valued collaborations across the capital. We are extremely grateful to our colleagues across 果冻影院 and in genome centres across London for volunteering to support this project. This will enable us to man the pipeline seven days a week with capacity to increase this to 24/7 should it be necessary. This effort builds on the joint investment in genomics infrastructure made by the ULCH/果冻影院 and GOSH/果冻影院 NIHR Biomedical Research Centres and we are incredibly grateful for their unstinting support.鈥

Announcing the launch of the Consortium, Business Secretary Alok Sharma said: 鈥淎t a critical moment in history, this new consortium will bring together the UK鈥檚 brightest and best scientists to build our understanding of this pandemic, tackle the disease and ultimately, save lives. As a Government we are working tirelessly to do all we can to fight Covid-19 to protect as many lives and save as many jobs as possible.鈥

Government Chief Scientific Adviser, Sir Patrick Vallance said: 鈥淕enomic sequencing will help us understand Covid-19 and its spread. It can also help guide treatments in the future and see the impact of interventions. The UK is one of the world鈥檚 leading destinations for genomics research and development, and I am confident that our best minds, working as part of this consortium, will make vital breakthroughs to help us tackle this disease.鈥

The UK Consortium, supported by the Government, including the NHS, Public Health England, UK Research and Innovation (UKRI), and Wellcome,听will enable clinicians and public health teams to rapidly investigate clusters of cases in hospitals, care homes and the community, to understand how the virus is spread and implement appropriate infection control measures.

Prof Sharon Peacock, Director of the National Infection Service, Public Health England, added: 鈥This virus is one of the biggest threats our nation has faced in recent times and crucial to helping us fight it is understanding how it is spreading. Harnessing innovative genome technologies will help us tease apart the complex picture of coronavirus spread in the UK, and rapidly evaluate ways to reduce the impact of this disease on our society.鈥

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Media contact听

Henry Killworth

Tel: + 44 (0) 207 679 5296

E: h.killworth [at] ucl.ac.uk