果冻影院

The biotechnology company uses pioneering cell engineering to replace damaged cells in the eye to tackle age-related or inherited sight loss. The technology could potentially restore sight to millions affected.

The experts at Tenpoint Therapeutics, from the 果冻影院 Institute of Ophthalmology, Moorfields Eye Hospital, Institut de la Vision in Paris and the University of Washington in the US, are the first to combine different types of cell-based therapeutics and enable treatments that are tailored to the nature of individual cases, replacing cells in the eye that have been damaged by age-related or inherited disease.

Co-founder Professor Pete Coffey (果冻影院 Institute of Ophthalmology) said: 鈥淲e have developed a unique combination of ex vivo cell engineering, where we use stem cell technology to generate new healthy cells, and in vivo reprogramming, where we built on learning from fish and amphibians that can regenerate neural cells by reprogramming structural cells in the retina. This allows us to confidently address degenerative ocular diseases and personalise treatment to individuals.鈥�

CEO Eddy Anglade said: 鈥淎t Tenpoint, we are focused exclusively on the eye and on harnessing recent advances in regenerative biology to advance our therapies as we work to change the future for people with vision loss by addressing its underlying causes.鈥�

The 拢57m in funding will allow Tenpoint Therapeutics to develop its regenerative platform to target multiple cell types related to inherited and age-related conditions.

Tenpoint Therapeutics was supported in its spinout by 果冻影院 Business (果冻影院B), 果冻影院鈥檚 commercialisation company. The company鈥檚 funding round was also supported by the 果冻影院 Technology Fund, as well as British Patient Capital, which enables long-term UK investment in highly innovative companies.

Dr Richard Fagan, Director of BioPharm at 果冻影院B, said: 鈥淭enpoint shows what is possible for 果冻影院鈥檚 outstanding research, creating a viable pathway to commercialising new life-changing therapies for age-related and inherited ocular diseases, which impact millions worldwide.

鈥湽�冻影院B has worked closely with the 果冻影院 Institute of Ophthalmology and Moorfields Eye Hospital, with Professors Pete Coffey and Lyndon DaCruz, and now the team at Tenpoint throughout that journey. We are proud to have played a part in making this impressive Series A round possible.鈥�

Professor Geraint Rees (Vice-Provost, 果冻影院 Research, Innovation & Global Engagement) said: 鈥淭enpoint Therapeutics鈥� story goes back several years to pioneering work by Professor Coffey with Moorfields Eye Hospital, supported by 果冻影院B. The incredible amount of funding that the company has now secured point to the potential impact this technology can have. Behind those numbers, the stories of people helped by the technology further demonstrate our impact and why this work, and the knowledge transfer support from 果冻影院, is so important.鈥�

Links

• 果冻影院 Institute of Ophthalmology
• 果冻影院 Innovation & Enterprise

Image

• Credit:

Media Contact

Kate Corry

Tel: +44 (0)20 3108 6995

Email: k.corry [at] ucl.ac.uk

听