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Vibrant images showcase key moments of discovery in 果冻影院 research

29 February 2024

Eye-catching images by researchers at 果冻影院 and Great Ormond Street Hospital (GOSH) that highlight 鈥淎 Moment of Discovery鈥 have been showcased as part of an annual competition.

The explosive potential of GI organoids

The winning image was submitted by PhD student, Giada Benedetti (果冻影院 Great Ormond Street Institute of Child Health), and shows 鈥淭he explosive potential of gastrointestinal organoids鈥.

For the third National Institute for Health and Care Research GOSH Biomedical Research Centre (NIHR GOSH BRC) image competition, staff from the 果冻影院 Great Ormond Street Institute of Child Health and GOSH were invited to submit an image of their work that showed 鈥淎 Moment of Discovery鈥.

The competition was also open to staff at other children鈥檚 hospitals across the UK within the NIHR GOSH BRC paediatric Excellence Initiative.

The eleven images and GIFs offer glimpses into research that is helping to find new treatments for rare or complex conditions and hopes to transform the lives of seriously ill children and young people. They were presented to three panels 鈥 the GOSH Young Peoples Advisory Group for Research (YPAG), NIHR GOSH BRC stakeholders and the GOSH staff networks.

The top three images were selected and put to the public who voted for an overall winner via social media.

Image 鈥榳hat you kneed to know鈥. Entered by Chrissy Bolton, Soren Lomholt and Patricia Reis-Nis.

The winning image shows a gut 鈥渕ini-organ鈥, known as an organoid, that is a tiny copy of the digestive system.

During a process used to visualise specific proteins, one of the organoids exploded, revealing its inner workings.

These tiny organs are useful to model gastrointestinal diseases and are the perfect tool for scientists studying new therapies and testing new drugs in the laboratory.

In particular, the organoids can be derived directly from paediatric patients, and this offers the opportunity to test therapies that specifically benefit the child.

Image 鈥業t鈥檚 about seeing the world鈥. Entered by Reem Alkharji, PhD student.

Giada Benedetti said: 鈥淪ometimes it can be easy to lose sight of why we are performing research, but the close interactions with the hospital really help motivate and give a clear purpose for the work that we do in the lab.

鈥淭he image competition is an excellent way to spread awareness for the research and display our scientific findings more dynamically and artistically, which is something that is easily lost in our usual world of number and spreadsheets.鈥

Other notable images听included a picture of an embryonic eye stained for dystrophin and an image showing the cells in a knee joint of a child with arthritis.

Links

Images (top-bottom)

  • Image 鈥楾he explosive potential of gastrointestinal organoids鈥 entered by Giada Benedetti, PhD student.
  • Image 鈥榳hat you kneed to know鈥. Entered by Chrissy Bolton, Soren Lomholt and Patricia Reis-Nis.

  • Image 鈥業t鈥檚 about seeing the world鈥. Entered by Reem Alkharji, PhD student.

Media contact听

Poppy Tombs

E: p.tombs听[at] ucl.ac.uk